Andrographis paniculata plant, King of Bitters; Good for diabetes?

[Fabe18]

There is another type of plant for diabetic which my mum planted in the garden. None in our family had history of diabetes but we sort of planted it to give away. It's not bitter, it's minty, can been eaten raw like salad green. We have recommended to many ppl and all had positive results. Eat today, next morning test show reduced bloody sugar level. I'm not kidding. Even those who were dependent on medication replaced it with the daily consumption of this leaf.

The bitter ones I think it's called Misai Kucing.

[Justme123]

Experiments using the whole extract of Misai Kuching on laboratory rats produced a significant decrease in blood glucose concentration compared with that in a control group. Comparative experiments with glibenclamide (the standard anti-diabetic drug) showed that similar results could be obtained but only with very high dosage of Misai Kuching.10.

http://www.mykucingtea.com/Misai%20K...alidation.html

Misai Kuching Flower


Often there are no proper research to subtantiate the claims of our local herbs and they are often touted to cure A-Z diseases.

[Tham]

I believe this herb has anticancer as well as antibacterial properties.

[besitai2007]

There is no short cut. For starters cut down intake of all sugar/carbohydrate laden food; reduce weight; exercise. For pre-diabetes, just losing weight helps.

[Fabe18]

There is another type of plant for diabetic which my mum planted in the garden. None in our family had history of diabetes but we sort of planted it to give away. It's not bitter, it's minty, can been eaten raw like salad green. We have recommended to many ppl and all had positive results. Eat today, next morning test show reduced bloody sugar level. I'm not kidding. Even those who were dependent on medication replaced it with the daily consumption of this leaf.

The bitter ones I think it's called Misai Kucing.

Found the name to the plant I was describing : Sambung Nyawa (Gynura Procumbens)



http://mylittlevegetablegarden.blogs...ung-nyawa.html

Effects of an Ethanolic Extract of Gynura procumbens on Serum Glucose, Cholesterol and Triglyceride Levels in Normal and Streptozotocin-Induced Diabetic Rats
S I N G A P O R E M E D I C A L J O U R N A L

Aim of Study: The aim was to demonstrate the effects of the leaves of Gynura procumbens (Lour.) Merr. on blood sugar and lipid levels in experimental animals.

Methodology: We obtained an ethanolic extract of the leaves of G. procumbens and monitored the effects of an oral administration of (i) different single doses of the extract on oral glucose tolerance in streptozotocin-induced diabetic and normal rats and (ii) fourteen doses over 7 days on serum cholesterol and triglyceride levels in streptozotocin-induced diabetic rats. Metformin and glibenclamide were used as positive control drugs.

Results: The extract, at single doses of 50, 150 and 300 mg/kg orally, significantly suppressed the elevated serum glucose levels in diabetic rats; 150 mg/kg was found to be the optimum hypoglycaemic dose. The extract however did not significantly suppress the elevated serum glucose levels in normal rats, unlike glibenclamide. Metformin, but not glibenclamide, improved glucose tolerance in the diabetic rats. When the optimum dose was given to diabetic rats for 7 days, the extract significantly reduced serum cholesterol and triglyceride levels in these rats.

Conclusion: These results indicate that the leaves of G. procumbens may have biguanide-like activity.

SOURCE: http://www.sma.org.sg/smj/4101/articles/4101a2.htm

When the optimum dose was given to diabetic rats for 7 days, the extract significantly reduced serum cholesterol and triglyceride levels in these rats.

Seem to mean the leaves can also reduce cholesterol???? Any doctors in the house to decipher the finding?

[Fabe18]

Anyone has the Sambung Nyawa plant??? Can spare some.. Used to have in abundant in my little plant strip in my house but gone.... Some given away, some died, some eaten by the bunnies... Need to get some for a friend's parents who has diabetes...

Thanks in advance...

[LMei]

Someone said to soak ladies fingers in hot water then drink up the water. My mum is on supplements now and so far her diabetes is under control.

[kuma]

Someone said to soak ladies fingers in hot water then drink up the water. My mum is on supplements now and so far her diabetes is under control.

'Natural Cures that Enhance Diabetes Medications'...>>>Click Here For More Cures

"OKRA[Lady's Finger]: Cut up two or three pods of okra and soak them in a glass of water overnight. In the morning simply discard the okra and drink the water. The idea is that the mucousy water coats the stomach, slowing the absorption of carbohydrates, and slowing the increase in blood glucose levels. I took it a step further. I learned to cook the okra quickly by adding the whole pods to boiling water, then boiling them for just three minutes. It confines the mucous within the pod making it less messy to eat. I eat about eight pods a day and save the water it boiled in for sipping throughout the day or to use in soups."

[besitai2007]

If you are interested in plants that have healing properties, follow this Facebook pagehttps://www.facebook.com/localmedicinalplants?ref=hl

[Tham]

http://www.mykucingtea.com/Misai%20K...alidation.html

Misai Kuching Flower


Often there are no proper research to subtantiate the claims of our local herbs and they are often touted to cure A-Z diseases.

Misai kuching = Orthosiphon stamineus.


Complementary alternative medicine use among patients with type 2 diabetes
mellitus in the primary care setting: a cross-sectional study in Malaysia.

http://www.biomedcentral.com/1472-6882/13/148




Antidiabetic properties and mechanism of action of Orthosiphon stamineus
Benth bioactive sub-fraction in streptozotocin-induced diabetic rats.

http://www.ncbi.nlm.nih.gov/m/pubmed/23433053/



Effects of Orthosiphon stamineus aqueous extract on plasma glucose concentration
and lipid profile in normal and streptozotocin-induced diabetic rats.

http://www.ncbi.nlm.nih.gov/m/pubmed/1703497




Potent α-glucosidase and α-amylase inhibitory activities of standardized 50%
ethanolic extracts and sinensetin from Orthosiphon stamineus Benth as anti-
diabetic mechanism.

http://www.biomedcentral.com/1472-6882/12/176




Antihyperglycemic effect of orthosiphon stamineus benth leaves extract
and its bioassay-guided fractions.

http://www.mdpi.com/1420-3049/16/5/3787




Note that Misai kuching and Andrographis paniculata strongly inhibits liver P450
enzymes, including CYP 2C19 and CYP 3A4, so can cause drug interactions -
delay the clearance and increase blood levels of drugs which are also metabolized
vide these enzymes, including omeprazole (Losec), the gastric drug, barbiturates,
some SSRI antidepressants and diazepam (Valium).


In vitro modulatory effects of Andrographis paniculata, Centella asiatica
and Orthosiphon stamineus on cytochrome P450 2C19 (CYP2C19).


http://www.ncbi.nlm.nih.gov/m/pubmed/21093571





In vitro effects of active constituents and extracts of Orthosiphon stamineus on
the activities of three major human cDNA-expressed cytochrome P450 enzymes.

http://www.ncbi.nlm.nih.gov/m/pubmed/21276781

[Tham]

'Natural Cures that Enhance Diabetes Medications'...>>>Click Here For More Cures

"OKRA[Lady's Finger]: Cut up two or three pods of okra and soak them in a glass of water overnight. In the morning simply discard the okra and drink the water. The idea is that the mucousy water coats the stomach, slowing the absorption of carbohydrates, and slowing the increase in blood glucose levels. I took it a step further. I learned to cook the okra quickly by adding the whole pods to boiling water, then boiling them for just three minutes. It confines the mucous within the pod making it less messy to eat. I eat about eight pods a day and save the water it boiled in for sipping throughout the day or to use in soups."

Ladies finger = Abelmoschus esculentus.

Brassica rapa = Turnip family, Chinese cabbage.

Musa acuminata = Banana.



Role of Mediterranean diet, tropical vegetables rich in antioxidants, and sunlight
exposure in blindness, cataract and glaucoma among African type 2 diabetics.


'' Indeed, after rural-urban migration, these type 2 diabetics are exposed to epidemiologic,
demographic, and nutrition transition, with subsequent consequences such as obesity,
inappropriate diet (high salt, fat, sugar, cigarette, and alcohol consumption).

In conclusion, both regular intake of the Mediterranean Diet and the consumption of locally
grown vegetables including Brassica Rapa, dry beans, Abelmoschus esculentus, and
Musa acuminata rich in antioxidants could exert significant protective effects on blindness,
cataract, and glaucoma development in type 2 diabetics.

Aging, higher SES (socioeconomic status), male sex, physical inactivity, and exposure
to sunlight were identified as risk factors of ocular diabetic complications. ''


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359045/




Table 2 :
Relationship between sociodemographic, lifestyle, sun light and ocular diseases n (%).

http://www.ncbi.nlm.nih.gov/pmc/arti...05-02-231-t02/



Table 3 :
Relationship between ocular diseases and dietary patterns n (%)

http://www.ncbi.nlm.nih.gov/pmc/arti...05-02-231-t03/

[Tham]

First identification of α-glucosidase inhibitors from okra (Abelmoschus esculentus) seeds.

http://www.ncbi.nlm.nih.gov/m/pubmed/24079173/?



Antidiabetic and antihyperlipidemic potential of Abelmoschus esculentus (L.) Moench.
in streptozotocin-induced diabetic rats.

http://www.jpbsonline.org/article.as...aulast=Sabitha





Water-soluble Fraction of Abelmoschus esculentus L Interacts with Glucose and Metformin
Hydrochloride and Alters Their Absorption Kinetics after Coadministration in Rats.


'' The results of this study indicate that A. esculentus may improve glycemic control
but should not be taken concurrently with metformin hydrochloride in controlling
diabetes mellitus. ''

http://www.hindawi.com/journals/isrn...s/2011/260537/